Fig. 8.

Conformational dynamics of unphosphorylated and phosphorylated Ras in complex with RafRBD. RMSDs of Cα atoms in unphosphorylated (black) and phosphorylated (red) systems within (A) all Ras and RafRBD residues; (B) Ras switch I residues, and (C) Ras switch II residues. Gray and pink transparencies represent the error. (D) RMSF of Ras residues. The two switch regions are marked with blue and yellow backgrounds. (E) RMSF of RafRBD residues. L4 loop region is marked with green background. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)