Table 4.
Linear regression models for the association between tertiles of IL-6 and CRP and body dissatisfaction and weight and shape concerns at age 14 years (n = 2,901).
| Outcomes | Exposure: third of IL-6 | Exposure: third of CRP | ||
|---|---|---|---|---|
| 2nd third (vs 1st) Mean difference (95%CI) in outcome |
3rd third (vs 1st) Mean difference (95%CI) in outcome |
2nd third (vs 1st) Mean difference (95%CI) in outcome |
3rd third (vs 1st) Mean difference (95%CI) in outcome |
|
| Body dissatisfaction | ||||
| Univariable | 1.66 (1.00, 2.32) p < 0.0001 | 2.48 (1.68, 3.30) p < 0.0001 | 2.60 (1.96, 3.24) p < 0.0001 | 4.11 (3.28, 4.92) p < 0.0001 |
| Multivariable model1 | 0.01 (-0.59, 0.62) p = 0.96 | 0.06 (-0.70, 0.82) p = 0.88 | 0.54 (-0.07, 1.16) p = 0.08 | 0.22 (-0.61, 1.05) p = 0.60 |
| Multivariable model2 | −0.06 (-0.66, 0.55) p = 0.61 | 0.01 (-0.75, 0.76) p = 0.98 | 0.55 (-0.07, 1.17) p = 0.08 | 0.22 (-0.61, 1.05) p = 0.60 |
| Weight & shape concerns | ||||
| Univariable | 0.41 (0.25, 0.57) p < 0.0001 | 0.65 (0.46, 0.84), p < 0.0001 | 0.62 (0.47, 0.78) p < 0.0001 | 0.91 (0.72, 1.10) p < 0.0001 |
| Multivariable model1 | 0.03 (-0.11, 0.17) p = 0.64 | 0.09 (-0.08, 0.27), p = 0.28 | 0.14 (-0.01, 0.29), p = 0.05 | 0.03 (-0.16, 0.22) p = 0.76 |
| Multivariable model2 | 0.01 (-0.13, 0.15), p = 0.84 | 0.08 (-0.10, 0.25) p = 0.38 | 0.15 (0.01, 0.29) p = 0.05 | 0.03 (-0.16, 0.22) p = 0.75 |
Multivariable model 1: adjusted for sex and total fat mass at age 9 years. Multivariable model 2: adjusted for sex, total fat mass at age 9 years, maternal education, maternal age at child’s birth, maternal pre-pregnancy BMI, maternal depression in pregnancy, mental health difficulties (i.e., total strength and difficulties questionnaire score) at age 7 years, peer victimization at age 8 years, maternal experience of stressful life events in pregnancy.