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. 2021 Feb 10;12:622233. doi: 10.3389/fgene.2021.622233

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Copyright © 2021 Wang, Zhao and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification and validation of a risk model to prognose LUAD patients. (A) The LASSO analysis model was verified by repeated calculation of the 16 m⁶A genes. (B) LASSO coefficient profiles. (C) According to LASSO risk factors, LUAD patients were divided into high-risk group and low-risk group. Heatmap demonstrated the expression levels of HNRNPA2B1, HNRNPC, KIAA1429, RBM15, and METTL3 in the two assessed groups. (D) Kaplan Meier analysis for the survival of LUAD patients. (E) 1-year (P < 0.001), (F) 3-year (P < 0.001), (G) 5-year OS ROC curves (P < 0.001).