Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 10;12:618773. doi: 10.3389/fphar.2021.618773

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Choi, Mohamad Zobir, Alexander-Dann, Sharma, Ma, Lam, Yeo, Zhang, Fan and Bender.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Pathway level interaction network of 10 highly enriched pathways in the ginsenoside Rb2/Rg3 combination-treated cells annotated according to ConsensusPathDB compared to control, providing synergy hypotheses of the compound combination. Node size is based on number of genes represented in each pathway gene set, color is determined by statistical enrichment value (darker blue = higher p value) and edge thickness represents the total number of genes shared between each pathway. (Detailed information about each pathway and its p value can be seen in Table 2.) It can be seen that growth factor receptor-mediated pathways such as EGFR1 and PDGF are major signaling that may contribute promoting effects on endothelial cell proliferation. Also, other pathways which are AP1, autophagy differentiation pathways are also known to be involved in regulating cell growth.