TABLE 3.

Gene Ontology analysis of Biological Processes of 94 genes found in the White Module, which is not conserved with the control network and contains the highest number of differentially expressed genes that correlated highly with the modules. It shows that this module is enriched in cell survival and angiogenesis signaling pathways, and hence these genes are of significant interest in determining the combination mode of action.

Term	Description	p-value
GO:0097191	Extrinsic apoptotic signaling pathway	0.0147
GO:0001525	Angiogenesis	0.0169
GO:0090050	Positive regulation of cell migration involved in sprouting angiogenesis	0.0304
GO:0008152	Metabolic process	0.0380
GO:0097105	Presynaptic membrane assembly	0.0390
GO:0070886	Positive regulation of calcineurin-NFAT signaling cascade	0.0390
GO:0043085	Positive regulation of catalytic activity	0.0496