FIGURE 4.

Staining and quantification of MBP at the anterior level. Numbered polygons in stained sections indicate neuroanatomical parcellations. (A–D) In the cingulate cortex (Cg), AdKO_2.0 mice had a male-specific increase in MBP-positive area compared to WT mice. (E,F) In the somatosensory cortex (S2), there was a reduction in MBP-immunopositive area in AdKO_2.0 mice of both sexes. S, G, and S × G: p value of the source of variation (sex, genotype, and interaction, respectively). Black dots: wild type. Gray squares: AdKO_2.0.