Figure 4.
Food intake after stress in wild-type, HSL KO, and HSL KO mice with mediobasal hypothalamic (MBH) overexpression of HSL. A) Graphic representation of hypothalamic HSL overexpression. B) HSL expression in laser-captured microdissected Arc and VMH. C) Food intake after injection stress and D) gene expression in laser-captured microdissected Arc in wild-type, HSL KO control, and HSL KO mice with hypothalamic overexpression of HSL by AAV. Data are mean ± SEM (n = 12). ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001 based on Student's unpaired t test (B) or one-way analysis of variance followed by Tukey's multiple comparisons test (C and D).