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. 2020 Jul 1;2(1):e000053. doi: 10.1136/bmjno-2020-000053

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Regressions of R₂ with CBF (n=67). Results are shown for six brain ROIs associated with particular structures. For each ROI, results are shown for CBF values derived from grey or white matter. The coefficient of determination, R², of the multiple linear regression model is reported with the symbol *, indicating significance at p<0.01. All ROIs exhibited significant positive correlations between R₂ and CBF. Note that analysis was restricted to WM ROIs for R₂ and to cortical GM or WM for CBF. CBF, cerebral blood flow; R₂, transverse relaxation rate; ROI, region of interest.