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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Bioorg Med Chem. 2020 Nov 28;30:115893. doi: 10.1016/j.bmc.2020.115893

Table 2.

Growth percentage values of compounds 1-7, 10, and 12 from NCI-60 human tumor cell line screen one-dose assay.

Growth %
Compound A549/ATCC EKVX HOP-62 HOP92 NCI-H226 NCI-H23 NCI-H322M NCI-H460 NCI-H522 Average
1 70.78 89.40 84.22 66.99 92.61 88.32 87.60 85.07 50.99 79.55
2 64.07 91.44 85.95 79.18 82.65 88.91 86.40 85.63 63.70 80.88
3 62.32 82.70 67.18 67.47 81.89 77.85 84.40 75.28 56.58 72.85
4 49.31 58.07 54.76 68.41 82.03 44.04 90.05 38.24 43.40 58.70
5 41.68 47.15 57.01 66.04 72.59 45.32 86.17 30.48 35.74 53.91
6 38.64 37.30 55.83 59.93 69.59 30.46 76.24 24.59 33.07 47.29
7 26.68 27.92 32.56 n/a 59.45 14.44 58.62 14.63 5.87 30.02
10 18.55 13.71 −4.86 −23.56 39.46 5.67 34.54 11.00 −72.29 2.47
12 −74.19 −62.61 −58.01 −68.19 −42.06 −80.31 −18.39 −69.88 −74.23 −60.87