Table 3.
All patients helmet CPAP N = 306 | Successful helmet CPAP treatment N = 159 | Helmet CPAP failure N = 147 | P value | |
---|---|---|---|---|
PaO2/FiO2 ratio, mmHg | 202 [146–284] | 252 [186–316] | 166 [114–243] | < 0.001* |
PaCO2, mmHg | 33 [30.5–36] | 33.2 [31–36.2] | 32.5 [30–35.2] | 0.091 |
Resp rate, BPM | 24 [20–29] | 22 [19–25] | 28 [20–32] | 0.007* |
PEEP, cm H2O | 5 [5–10] | 5 [5–8] | 5 [5–10] | 0.010* |
PaO2/FiO2 ratio increase with CPAP, mmHg | 83 [28–154] | 96 [45–176] | 53 [18–115] | < 0.001* |
ARDS diagnosis, n (%) | 178 (71) | 78 (62) | 100 (79) | 0.006* |
Univariate analysis of the association of respiratory parameters collected shortly after CPAP start with CPAP failure during hospital stay
BPM: breaths per minute; PEEP: positive end expiratory pressure; CPAP: continuous positive airway pressure; ARDS: acute respiratory distress syndrome. Asterisks (*) indicates statistically significant differences after Bonferroni correction for multiple comparisons (p < 0.009)