Table 4.

Reasons for withdrawals by treatment

	All withdrawals (n=80)	During a placebo period (n=39)	During a statin period (n=34)	Neither (n=7)
Withdrawal of consent	16 (8)	8 (4)	7 (3.5)	1 (0.5)
Muscle symptoms*	1 (0.5)	1 (0.5)	0	0
Non-muscle symptoms*	4 (2)	2 (1)	2 (1)	0
Not related to drug treatment*	3 (1.5)	1 (0.5)	2 (1)	0
Switched to statin*	0	0	0	0
No reason given*	8 (4)	4 (2)	3 (1.5)	1 (0.5)
Intolerable muscle symptoms	32 (16)	13 (6.5)	18 (9)	1 (0.5)
Clinical concern	14 (7)	9 (4.5)	4 (2)	1 (0.5)
Muscle symptoms*	1 (0.5)	1 (0.5)	0	0
Non-muscle symptoms*	4 (2)	2 (1)	2 (1)	0
Not related to drug treatment*	5 (2.5)	3 (1.5)	2 (1)	0
Switched to statin*	4 (2)	3 (1.5)	0 (0)	1 (0.5)
Other	17 (8.5)	8 (4)	5 (2.5)	4 (2)
Non-muscle symptoms*	4 (2)	4 (2)	0	0
Not related to drug treatment*	13 (6.5)	4 (2)	5 (2.5)	4 (2)
Unknown	1 (0.5)	1 (0.5)	0	0

Data are number (%) of participants from 200 participants randomised to a sequence of treatments.

^*Post hoc finer categorisation.