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. 2021 Feb 19;21(4):371. doi: 10.3892/etm.2021.9802

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Copyright: © She et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Immunohistochemical staining of MMP-2 and ERK1/2. (A) Immunohistochemical staining of ERK1/2. (B) Immunohistochemical staining of MMP2. Brown staining (red arrows) represents the location of MMP-2 or ERK1/2 and blue staining represents the cell nucleus (scale bar, 100 µm for the top row and 50 µm for the bottom row; magnification, x200 for the top row and x400 for the bottom row). ERK1/2 was mainly found in the cytoplasm of SFs, INL and RGCs. MMP-2 was mainly localized in the cytoplasm and the extracellular matrix of SFs, INL and RGCs. SFs, scleral fibroblasts; INL, inner nuclear layer; RGCs, retinal ganglion cells.