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. 2021 Feb 8;21(4):331. doi: 10.3892/etm.2021.9762

Figure 2.

Figure 2

Pemafibrate reduces mitochondrial dysfunction in H9c2 cells following H/R. (A) Protein expression levels of PPARα under HG or HG + H/R conditions were detected by western blotting. **P<0.01 vs. control; #P<0.05 vs. HG. (B-E) Relative levels of (B) ATP, (C) mtROS, (D) MDA and (E) SOD were determined using commercial assay kits. ***P<0.001 vs. control; ##P<0.01, ###P<0.001 vs. HG + H/R. HG, high glucose; H/R, hypoxia/reperfusion; MDA, malondialdehyde; mtROS, mitochondrial reactive oxygen species; PPARα, peroxisome proliferator-activated receptor α; SOD, superoxide dismutase.