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. 2021 Feb 13;21(4):359. doi: 10.3892/etm.2021.9790

Figure 4.

Figure 4

miR-874-3p mediates GC apoptosis via HDAC1 inhibition. (A) Following transduction with lentiviral vectors expressing miR-874-3p mimic, mimic NC, inhibitor or inhibitor NC for 24 h, HDAC1 mRNA expression levels in mouse GCs were measured via reverse transcription-quantitative PCR. Following transduction with the HDAC1 overexpression vector or the control empty vector for 24 h, then transduction with miR-874-3p inhibitor or inhibitor NC for 24 h, mouse GC apoptosis was (B) determined via flow cytometry and (C) quantified. *P<0.05. miR, microRNA; GC, granulosa cell; HDAC, histone deacetylase.