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. 2021 Feb 6;22:101327. doi: 10.1016/j.pmedr.2021.101327

Table 3.

Relationship between knowledge and attitude scores regarding folic acid supplement recommendations during pregnancy.

Statement Attitude n (%) KS1 p-value KS2 p-value TKS p-value
I am familiar with the most recent Agree 24 (31.2) 2.0 ± 0.24 0.42 4.8 ± 0.25 0.58 6.8 ± 0.34 0.35
guideline Unsure 25 (32.5) 1.6 ± 0.23 4.6 ± 0.25 6.2 ± 0.34
Disagree 28 (36.4) 1.8 ± 0.22 4.4 ± 0.24 6.3 ± 0.32
There could be potential adverse effects Agree 21 (27.3) 2.0 ± 0.26 0.45 4.7 ± 0.27 0.57 6.6 ± 0.37 0.26
due to high FA intake during pregnancy Unsure 31 (40.3) 1.6 ± 0.21 4.4 ± 0.22 6.0 ± 0.30
Disagree 25 (32.5) 2.0 ± 0.23 4.8 ± 0.25 6.7 ± 0.34
High FA intake may negatively modify fetal Agree 15 (19.5) 1.9 ± 0.30 0.87 4.6 ± 0.32 0.21 6.5 ± 0.44 0.54
development Unsure 36 (46.8) 1.75 ± 0.2 4.8 ± 0.21 6.6 ± 0.28
Disagree 26 (33.8) 1.8 ± 0.23 4.3 ± 0.24 6.2 ± 0.33
Most PVS contain the recommended Agree 58 (75.3) 2.0 ± 0.14a,c 0.004 4.5 ± 0.16 0.42 6.6 ± 0.22 0.40
amount of FA Unsure 9 (11.7) 0.7 ± 0.37a 5.1 ± 0.41 5.8 ± 0.56
Disagree 10 (13.0) 1.7 ± 0.35b,c 4.5 ± 0.4 6.2 ± 0 0.53
My recommendations are in line with the Agree 47 (61.0) 2.0 ± 0.17 0.32 4.6 ± 0.18 0.57 6.6 ± 0.25 0.65
most recent guideline Unsure 28 (36.4) 1.6 ± 0.22 4.5 ± 0.24 6.2 ± 0.32
Disagree 2 (2.6) 1.0 ± 0.82 5.5 ± 0.88 6.5 ± 1.20
I’m comfortable recommending PVS that Agree 12 (15.6) 1.9 ± 0.34 0.82 5.2 ± 0.35 0.19 7.1 ± 0.48 0.26
are not in line with the guideline Unsure 23 (29.9) 1.7 ± 0.25 4.4 ± 0.26 6.1 ± 0.35
Disagree 42 (54.6) 1.9 ± 0.18 4.5 ± 0.19 6.4 ± 0.26

P values were estimated using general linear models with Tukey’s post hoc test for subgroup comparisons. The letters indicate which attitude subgroups in response to statements were found to differ significantly. Subgroups with the same letters do not differ significantly while those with different letters do. FA = folic acid; PVS = prenatal vitamin/mineral supplement.

*The total knowledge score (TKS) is the sum of knowledge sub-scores one and two (KS1 and KS2, respectively) and they are presented as means ± SE.