Table 2.
Validation cohort 1 | Validation cohort 2 | |||||||
---|---|---|---|---|---|---|---|---|
Variables | Univariate | Multivariate | Univariate | Multivariate | ||||
Odds ratio (CI) | p | Odds ratio (CI) | p | Odds ratio (CI) | p | Odds ratio (CI) | p | |
AGE | 1.06(1.00–1.11) | .036 | 1.04(0.93–1.17) | .47 | 1.05(.99–1.11) | .68 | ||
PSA | .97(0.87–1.07) | .54 | 1.05(1.00–1.11) | .52 | ||||
miR-26b-5p | .0001(.00–.002) | .0001 | .0001(.00–.48) | .0001 | .11(.001–.109) | <.0001 | .011(.001–.11) | .0001 |
miR-30c | .98(0.95–1.01) | .14 | .984(.96–1.101) | .27 | ||||
miR-21-5p | .99(0.99–1.00) | .21 | .99(.99–1.00) | .29 | ||||
miR-98-5p | .77(0.54–1.10) | .160 | .68(.43–1.09) | .11 | ||||
miR-4732-3p | 6.60(2.46–17.37) | .0001 | 1.82(.55–6.04) | .33 | 1.53(1.01–2.33) | .04 | .98(0.59–1.69) | .94 |
Let7a-5p | .99(.98–1.00) | .117 | .99(.97–1.00) | .16 |
Abbreviations CI, Confident Interval, p p value, PSA Prostate Specific Antigen. Data are presented as odds ratio (CI). Empty cells correspond to variables that were not measured. Baseline variables that achieved a level of significance of p < .05 in the univariate analysis were entered into multivariate models