Table 1.
Demographic background and clinical characteristics of the participants
| Placebo-administered group (N = 40) | Oxytocin-administered group (N = 43) | Oxytocin versus placebo group | Time-course change group (N = 20) | Time-course change versus placebo group | ||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | p valuec | Mean | SD | p valuec | |
| Age (range) | 26.4 (18–46) | 6.9 | 28.2 (18–48) | 7.4 | 0.26 | 30.9 (22–47) | 6.6 | 0.02 |
| Height, cm | 172.2 | 5.7 | 170.5 | 6.4 | 0.21 | 170.5 | 6.1 | 0.30 |
| Body weight, kg | 66.7 | 11.5 | 67.3 | 11.5 | 0.80 | 69.5 | 11.2 | 0.37 |
| SESa | 2.8 | 1.2 | 3.2 | 1.0 | 0.08 | 3.3 | 1.1 | 0.12 |
| Parental SESa | 2.2 | 0.6 | 2.2 | 0.6 | 0.66 | 2.1 | 0.6 | 0.75 |
| Handedness: Right/left | 37/3 | 41/2 | 20/0 | |||||
| IQb | ||||||||
| Full IQ | 110.3 | 14.1 | 105.2 | 13.7 | 0.10 | 106.4 | 14.6 | 0.31 |
| Verbal IQ | 116.5 | 14.3 | 110.7 | 13.2 | 0.06 | 110.8 | 13.4 | 0.14 |
| Performance IQ | 100.2 | 14.7 | 96.5 | 15.4 | 0.27 | 98.1 | 16.3 | 0.61 |
| ADIR | ||||||||
| Social | 21.9 | 5.2 | 21.2 | 5.0 | 0.57 | 21.7 | 4.4 | 0.91 |
| Communication | 16.3 | 3.4 | 15.6 | 3.9 | 0.36 | 15.8 | 3.6 | 0.56 |
| Repetitive | 5.9 | 2.3 | 5.3 | 2.6 | 0.36 | 5.3 | 2.6 | 0.41 |
SES, socioeconomic status; IQ, intelligence quotient; SD, standard deviation; ADIR, Autism Diagnostic Interview—Revised
aSES assessed using the Hollingshead scale. Higher scores indicate lower status
bIntelligence quotients were measured using the Wechsler Adult Intelligence Scale
cp values were calculated using the independent t-test