Fig. 5.

Computational simulation of a multi-agent object. a Illustration of the general model. b Snapshot of a simulated sphere cut in half. c Piecewise exponential-linear fit (black dashed lines) to the growth rates for the long-term single-cell analysis of mPOs. The colours resemble organoids shown in Fig. 3. The dots indicate the cell count of the organoids. The coloured dashed lines indicate the transition from exponential to linear growth. d Volumes of the simulated organoids. The coloured dashed lines indicate the transition from an exponential to a linear growth rate. The coloured solid lines show the volumes of the spheres