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Entinostat treatment attenuated hematoma volume on day 3 post-ICH. To assess hematoma volume, the brain hemoglobin content and SW-MRI were performed at 72 h post-ICH as described in methods. Entinostat treatment significantly reduced the (A) ipsilateral brain hemoglobin content (ICH+ vehicle; n=3 and ICH+ Entinostat; n=4) and (B&C) hematoma volume as assessed by SW-MRI (n= 4/group).
