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. Author manuscript; available in PMC: 2021 Feb 24.
Published in final edited form as: Ann Neurol. 2020 Nov 7;89(2):254–265. doi: 10.1002/ana.25948

Figure 5. Area Deprivation Index (ADI) mediates the relationship between race and Alzheimer Disease (AD) signature volume.

Figure 5.

The effect of being African American compared to White on the AT(N) measures is shown as the total race effect. The total effect is a sum of the direct and indirect effects. The direct effect indicates the size of the effect not explained by any of the mediating factors. The indirect effect indicates the size of the effect explained by the mediating factors. 95% confidence intervals are also shown.

ADI = Area Deprivation Index; WMH = white matter hyperintensities; BP = blood pressure; BMI = body mass index