Volumetric, resting-state connectivity, and blood flow signatures of frailty in persons living with HIV. Brain regions and networks associated with frailty identified in the linear GBM from superior (A), inferior (B), right hemisphere (C), left hemisphere(D), rostral (E), and caudal (F) perspectives. Darker shades of color represent a higher rank order (mutual information criterion) of the individual feature. Image created using BrainNet Viewer [43].