TABLE 1.
Demographic and Clinical Characteristics
| Variable | Frail (n = 20) | Nonfrail (n = 85) | P |
|---|---|---|---|
| Demographic | |||
| Age (yrs) (SD) | 55.2 (8.31) | 55.8 (7.26) | 0.76 |
| Sex (% male/female) | 70% | 88% | 0.04 |
| Race (% African American) | 70% | 58% | 0.11 |
| Education (yr) (SD) | 12.5 (2.53) | 13.6 (2.7) | 0.11 |
| HIV disease | |||
| Duration of HIV infection (mo) (SD) | 214 (85) | 209 (107) | 0.83 |
| Undetectable viral load (<50 copies/mL), % | 85% | 91% | |
| Current CD4 count (cells/mm3), median (IQR) | 688 (348.9) | 528 (248.9) | 0.02 |
| Nadir CD4 count (cells/mm3), median (IQR) | 230 (200.0) | 91 (182.36) | 0.05 |
| Health comorbidities | |||
| Affective BDI-II subscale (SD) | 4.0 (2.9) | 1.7 (2.0) | 0.003 |
| Hepatitis C coinfection, % | 25% | 12% | 0.13 |
| Neurocognitive performances | |||
| Global: mean (SD) | −0.44 (0.7) | −0.25 (0.6) | 0.22 |
| Executive function: mean (SD) | −0.54 (0.7) | −0.33 (0.7) | 0.21 |
| Psychomotor/Processing speed: mean (SD) | −0.31 (0.8) | 0.02 (0.7) | 0.07 |
| Memory: mean (SD) | −0.71 (1.1) | −0.39 (0.9) | 0.19 |
| Learning: mean (SD) | −0.76 (1.0) | −0.53 (0.9) | 0.33 |
| Language: mean (SD) | 0.12 (1.0) | −0.04 (0.8) | 0.47 |
Bold indicates P < 0.05.
IQR, interquartile rating.