Table 3.
The Nomogram C-Index for OS and Other Predictors
| Training Cohort | Validation Cohort | |||||
|---|---|---|---|---|---|---|
| Predictors | C-Index | 95% CI | P value | C-Index | 95% CI | P value |
| Nomogram | 0.752 | 0.706–0.798 | 0.701 | 0.654–0.748 | ||
| APRI | 0.568 | 0.535–0.601 | <0.001 | 0.537 | 0.503–0.571 | <0.001 |
| Blood loss | 0.593 | 0.560–0.626 | <0.001 | 0.552 | 0.519–0.585 | <0.001 |
| Tumor number | 0.520 | 0.508–0.532 | <0.001 | 0.500 | 0.486–0.513 | <0.001 |
| Tumor size | 0.651 | 0.613–0.689 | <0.001 | 0.620 | 0.582–0.658 | <0.001 |
| MVI | 0.632 | 0.597–0.668 | <0.001 | 0.592 | 0.557–0.627 | <0.001 |
| Satellite lesions | 0.593 | 0.558–0.628 | <0.001 | 0.608 | 0.574–0.643 | <0.001 |
| Livers cirrhosis | 0.538 | 0.498–0.578 | <0.001 | 0.516 | 0.475–0.556 | <0.001 |
| TNM stage | 0.664 | 0.624–0.704 | <0.001 | 0.609 | 0.570–0.648 | <0.001 |
| BCLC stage | 0.550 | 0.524–0.577 | <0.001 | 0.533 | 0.508–0.557 | <0.001 |
Notes: P value: nomogram versus other predictors. P<0.05 was defined as statistical significance.
Abbreviations: C-index, concordance index; OS, overall survival; CI, confidence interval; APRI, aspartate aminotransferase-to-platelet ratio index; MVI, microvascular invasion; BCLC, Barcelona Clinic Liver Cancer; TNM, TNM Classification of Malignant Tumors.