Table 2. Bacteremia in AGMs and RMs following inhalation of B. pseudomallei HBPUB10134a.
| Prevalence | Mean(SE)c | |||
|---|---|---|---|---|
| Day Post-Infection | AGM | RM | AGM | RM |
| 1 | 1 / 5 | 0 / 5 | 2.85 (0.62) | 0 |
| 2 | 1 / 5 | 1 / 5 | 2.85 (0.62) | -0.18 (0.97) |
| 3 | 2 / 5 | 0 / 5 | 2.85 (0.62)a | 0 |
| 4 | 3 / 5 | 0 / 5 | 3.90 (0.62) | 0 |
| 5 | 4 / 4 | 0 / 5 | 3.52 (0.69) | 0 |
| 6 | 1 / 2 | 1 / 5 | 4.03 (0.98) | 0.30 (1.07) |
| 7 | 2 / 2 | 0 / 5 | 4.31 (0.98) | 0 |
| Terminal Bleed | 4 / 5 | 2 / 5b | 4.04 (0.61) | 4.66 (0.59) |
aOne animal with “too numerous to count” values at all dilutions was imputed to 3500 CFU/mL.
bTerminal end point for RMs was day 46 or day 47 except for one RM with day 13 as terminal end point. The median time to death in the AGM group was 5 days (95% CL5.0–13.0).
cMean Log10 CFU/mL for blood and urine, or Log10 CFU/g tissue for other organs. SE represents standard error computed under a negative binomial model.