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. 2021 Feb 24;16(2):e0247591. doi: 10.1371/journal.pone.0247591

Table 5. Modelling the determinants of correct drug match at the medicine level.

Predictor Model 1 Model 2 Model 3
Drug Characteristics
Drug Class
Analgesic - - -
Antacid 0.07*** [0.03–0.18] 0.07*** [0.02–0.17] 0.07*** [0.03–0.18]
Anti-Asthmatic 0.21 [0.03–1.70] 0.22 [0.03–1.83] 0.22 [0.03–1.87]
Anti-Diabetic 0.13** [0.03–0.46] 0.12** [0.03–0.46] 0.12** [0.03–0.45]
Antihistamine 0.01*** [0.01–0.02] 0.01*** [0.01–0.02] 0.01*** [0.01–0.02]
Anti-Hypertensive 0.19*** [0.10–0.37] 0.23*** [0.10–0.54] 0.23*** [0.10–0.54]
Anti-Hypertensive##Treatment 9.95** [1.88–52.69]
Anti-Hypertensive##Being insured 25.15*** [4.17–151.61]
Anti-Malarial 0.49* [0.27–0.89] 0.44* [0.24–0.82] 0.44* [0.24–0.83]
Anti-Spasmodic 0.06*** [0.02–0.19] 0.08*** [0.02–0.32] 0.08*** [0.02–0.33]
Antibiotic 0.04*** [0.03–0.06] 0.04*** [0.03–0.06] 0.04*** [0.03–0.06]
Antibiotic##Being insured 3.60** [1.45–8.92]
Expectorant 0.03*** [0.02–0.07] 0.03*** [0.01–0.06] 0.03*** [0.01–0.06]
Haematinic 0.05*** [0.03–0.07] 0.04*** [0.03–0.07] 0.04*** [0.03–0.07]
Haematinic##Treatment 2.32* [1.03–5.25]
Haematinic##Being insured 5.40*** [2.54–11.50]
Vitamin & Mineral 0.02*** [0.01–0.02] 0.01*** [0.01–0.02] 0.01*** [0.01–0.02]
Vitamin & Mineral##Being insured 3.76*** [1.88–7.53]
Place Drug was Obtained
Public health facility - -
Private health facility 2.01* [1.08–3.77] 2.04* [1.10–3.80]
Patent Proprietary Medicine Vendors 1.74* [1.05–2.90] 1.94* [1.15–3.25]
Other 1.37 [0.73–2.58] 1.51 [0.80–2.85]
Demographic characteristics
Age Group
0–18 - -
19–35 1.07 [0.71–1.61] 1.07 [0.71–1.62]
36–60 0.76 [0.51–1.13] 0.77 [0.52–1.15]
≥61 0.70 [0.47–1.04] 0.70 [0.47–1.04]
Gender
Male - -
Female 0.95 [0.77–1.16] 0.94 [0.77–1.15]
Socioeconomic characteristics
Marital Status
Single - -
Married 0.97 [0.70–1.35] 0.97 [0.70–1.34]
Household Size
1–5 - -
≥6 0.97 [0.73–1.29] 0.98 [0.73–1.30]
Education Level
No education - -
Primary 1.01 [0.80–1.28] 1.01 [0.79–1.28]
Secondary 0.85 [0.63–1.13] 0.86 [0.64–1.15]
Tertiary 1.63* [1.06–2.49] 1.61* [1.05–2.47]
Income Level
Quintile 1 (Poorest) - -
Quintile 2 1.13 [0.69–1.87] 1.13 [0.68–1.86]
Quintile 3 1.14 [0.72–1.80] 1.13 [0.72–1.79]
Quintile 4 1.38 [0.88–2.18] 1.37 [0.87–2.15]
Quintile 5 (Richest) 1.34 [0.85–2.09] 1.31 [0.84–2.06]
Health-related characteristics
Chronic Disease
No - -
At least one 0.95 [0.71–1.27] 0.93 [0.70–1.25]
Distance from Nearest Health Facility (Km) 0.98 [0.95–1.02] 0.98 [0.95–1.02]
Insurance program indicators
Observation in Treatment Area
No - -
Yes 1.51** [1.16–1.98] 1.41* [1.05–1.87]
Insurance Status
No -
Yes 1.26 [0.93–1.71]
Chi-square 835 892 892
df 11 30 31
Deviance 4,242 3,998 3,990
N 6,772 6,524 6,517

* p<0.05

** p<0.01

*** p<0.001 [95% Confidence Interval].

Results of fitting a series of logistic regression models predicting the likelihood of having a medicine use correctly match its actual clinical use, using drug class, and controlling for relevant covariates. Model 1: Drug class only, Model 2: Drug class and socio-demographic factors, Model 3: Drug class, socio-demographic and insurance status.