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. 2021 Feb 24;16(2):e0246601. doi: 10.1371/journal.pone.0246601

Fig 2. Analysis and comparison of atherosclerosis across time in ApoE-/-, with SCI, and Salsalate.

Fig 2

Aortic arch lesion area in ApoE-/- progressively increases over time and is significant at 24- and 28-weeks compared to 16- and 20-week (*). At 24- and 28-weeks, SCI (ApoE-/-SCI) lesion area is significantly greater than time-controlled ApoE-/- (^). Salsalate treatment (ApoE-/-SCI/sal) lesion area is significantly reduced at both 24- and 28-weeks compared to SCI (ApoE-/-SCI, ). *^p < 0.05.