Table 1.
D0 (Gy) | Dq (Gy) | SF2 | SER | |
---|---|---|---|---|
KD | 2.81 | 1.04 | 0.59 | 1.01 |
NC | 2.84 | 0.71 | 0.56 | |
OE | 1.85 | 0.46 | 0.41 | 1.54 |
Data are presented as the slope of the curve fitted. The radiation biologic parameters were calculated by GraphPad Prism 8.0 that was fitted into the single-hit multitarget formula:SF = 1 − (1 − exp(−k × x))N;k = 1/D0;lnN = Dq/D0;SER = D0 (control group)/D0 (experimental group). D0: final slope; Dq: quasi-threshold dose; SF2: 2 Gy of survival fraction (SF); SER: sensitization enhancement ratio; KD: low IL-32 expression; OE: overexpression IL-32.