Table 2.
D0 (Gy) | Dq (Gy) | SF2 | SER | |
---|---|---|---|---|
KD | 2.49 | 1.69 | 0.63 | 0.94 |
NC | 2.34 | 1.19 | 0.57 | |
OE | 2.15 | 0.3 | 0.40 | 1.09 |
Data are presented as the slope of the curve fitted. The radiation biologic parameters were calculated by GraphPad Prism 8.0 that was fitted into the single-hit multitarget formula: SF = 1 − (1 − exp(−k × x))N; k = 1/D0; lnN = Dq/D0; SER = D0 (control group)/D0 (experimental group). D0: final slope; Dq: quasi-threshold dose; SF2: 2 Gy of survival fraction (SF); SER: sensitization enhancement ratio; KD: low IL-32 expression; OE: overexpression IL-32.