Table 5.
The meta-analysis results of the secondary outcomes.
| Indication | Outcomes | Number of studies included | Cases | Heterogeneity test | Effect model | Results of the meta-analysis | ||
|---|---|---|---|---|---|---|---|---|
| I 2 | p | SMD/OR (95% CI) | p | |||||
| Acute PID | Clinical symptom remission or disappearance time | 8 | 899 | — | — | — | — | — |
| The time of the masses disappearance | 7 | 821 | 89.2% | 0.001 | R | −1.36 (−1.84, −0.89) | 0.001 | |
| The time of body temperature return to normal | 7 | 821 | 84.9% | 0.001 | R | −1.19 (−1.58, −0.79) | 0.001 | |
| The time to relieve abdominal pain | 7 | 821 | 90.7% | 0.001 | R | −1.83 (−2.38, −1.29) | 0.001 | |
| Serum inflammatory factor concentration | 6 | 558 | — | — | — | — | — | |
| CRP concentration | 3 | 300 | 92.1% | 0.001 | R | −1.99 (−3.01, −0.98) | 0.001 | |
| TNF-α concentration | 4 | 372 | 50.8% | 0.107 | F | −1.73 (−1.97, −1.49) | 0.001 | |
| IL-6 concentration | 4 | 380 | 94.4% | 0.001 | R | −1.53 (−2.52, −0.53) | 0.001 | |
| Chronic PID | Clinical symptom remission or disappearance time | 13 | 1394 | — | — | — | — | — |
| The remission time of uterine pain | 5 | 542 | 92.0% | 0.001 | R | −2.48 (−3.29, −1.66) | 0.001 | |
| The remission time of abdominal pain | 12 | 1208 | 85.6% | 0.001 | R | −2.12 (−2.49, −1.74) | 0.001 | |
| The time for leucorrhoea to return to normal | 7 | 782 | 27.4% | 0.219 | F | −1.38 (−1.54, −1.22) | 0.001 | |
| Serum inflammatory factor concentration | 11 | 2317 | — | — | — | — | — | |
| CRP concentration | 5 | 1575 | 87.6% | 0.001 | R | −3.10 (−3.69, −2.51) | 0.001 | |
| TNF-α concentration | 5 | 646 | 96.6% | 0.001 | R | −2.56 (−3.68, −1.43) | 0.001 | |
| IL-2 concentration | 3 | 264 | 0.0% | 0.969 | F | 0.85 (0.59, 1.10) | 0.001 | |
| IL-4 concentration | 3 | 264 | 0.0% | 0.933 | F | 0.60 (0.59, 0.85) | 0.001 | |
| IL-10 concentration | 2 | 182 | 0.0% | 0.790 | F | 0.49 (0.20, 0.79) | 0.001 | |
|
| ||||||||
| Endometritis | Endometrial thickness | 16 | 1680 | 87.8% | 0.001 | R | 2.25 (1.89, 2.60) | 0.001 |
| Normalization rate of menstrual | 12 | 1413 | 0.0% | 0.978 | F | 4.01 (3.04, 5.30) | 0.001 | |
| Normalization rate of menstrual cycle | 6 | 845 | 46.3% | 0.097 | F | 5.57 (3.82, 8.13) | 0.001 | |
| Normalization rate of menstrual amount | 6 | 865 | 79.9% | 0.001 | R | 4.96 (1.72, 14.28) | 0.001 | |
| Incidence of irregular vagina bleeding | 15 | 1693 | 0.0% | 0.995 | F | 0.23 (0.16, 0.31) | 0.001 | |
| 6-month relapse rate | 3 | 576 | 0.0% | 0.683 | F | 0.15 (0.07, 0.35) | 0.001 | |
FKQJP, Fuke Qianjin tablet; R, random-effect model; F, fix-effect model.