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Report of negative events in included studies (N=83).
| Report of negative events | Studies, n (%) |
| Dropout | 70 (84) |
| Deterioration | 21 (25) |
| Adverse events | 18 (22) |
| Nonresponse | 16 (19) |
| Severe adverse events | 14 (17) |
| Novel Symptoms | 0 (0) |
| Unwanted Events | 0 (0) |
