Fig. 12.

Molecular interaction of the ligand, Diosmin (6) with nsp15 protein is shown. Hydrogen bond interactions with aa residues (His235, Gln245, Gly248, His250, Lys290, and Glu340) are shown in right panel with yellow dotted line and pi-pi interaction with residue Tyr343 (blue dotted line), whereas the docked pose of ligand within crystal structure of nsp15 protein is shown in left panel. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)