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. Author manuscript; available in PMC: 2021 Jun 7.
Published in final edited form as: Nat Chem Biol. 2020 Dec 7;17(3):272–279. doi: 10.1038/s41589-020-00696-0

Figure 5 |. Molecular Dynamics simulations reveal pleiotropic structural effects on UBs harboring lysine analogs.

Figure 5 |

(a) Distribution of the distances between lysine acceptor amine and Cα atoms for UBC4 versus UBC5 in molecular dynamics (MD) simulations performed of UB. (b) Plot showing the dynamics of Chi4 side-chain rotomers for various UBC5 acceptors compared with UBC4. Bins are divided by 120° intervals. (c) same as (b), except for the psi main-chain torsion angle. Bins are divided by 10° intervals. (d) same as (b), except for the phi main-chain torsion angle. For all plots graphs, N=2 independent experiments.