A) Atherosclerosis was quantified in the aortic arch by Oil-Red-O staining and en face analysis. In the aortic sinus, plaques were assessed by B) H&E (size; scale bars = 100 μm), C) Oil-Red-O (lipid), D) CD68+ area (macrophages) and E) picrosirius red (collagen), scale bars: 50 μM. Data are presented mean ± SEM and analyzed using a Student’s unpaired t-test, biological replicates of n=6 & 7/group; *p<0.05, **p<0.01, ****p<0.0001.