Table 3.
HRs for KFRT According to Baseline Obesity Status by Sex and Race
| White (n/N = 95/10,222) |
Black (n/N = 95/3,274) |
|||
|---|---|---|---|---|
| Men (n/N = 57/4,802) | Women (n/N = 43/5,420) | Men (n/N = 39/1,270) | Women (n/N = 56/2,004) | |
| BMI, kg/m2 | 27.23 ± 3.86 | 26.33 ± 5.09 | 27.28 ± 4.53 | 30.29 ± 6.36 |
| HR per 1-SD greater BMIa | ||||
| Model 1 b,c | 1.26 (0.98-1.62) | 1.51 (1.14-2.01)d | 1.75 (1.29-2.36)e | 1.68 (1.33-2.13)e |
| Model 2b,c | 1.04 (0.79-1.39) | 1.06 (0.76-1.46) | 1.51 (1.09-2.11)f | 1.65 (1.29-2.13)e |
| WHR | 0.97 ± 0.05 | 0.89 ± 0.08 | 0.94 ± 0.05 | 0.90 ± 0.08 |
| HR per 1-SD greater WHRa | ||||
| Model 1 b,c | 1.12 (0.86-1.48) | 1.79 (1.26-2.53)d | 1.99 (1.38-2.87)e | 1.78 (1.32-2.40)e |
| Model 2b,c | 0.92 (0.69-1.23) | 1.26 (0.86-1.84) | 1.73 (1.18-2.53)d | 1.74 (1.26-2.40)d |
| Predicted % fat | 28.49 (3.88) | 39.99 (4.92) | 26.31 (4.65) | 41.83 (5.99) |
| HR per 1-SD greater predicted % fata | ||||
| Model 1 b,c | 1.19 (0.91-1.54) | 1.72 (1.31-2.26)d | 1.86 (1.36-2.55)d | 1.68 (1.32-2.14)d |
| Model 2b,c | 0.94 (0.71-1.25) | 1.27 (0.92-1.74) | 1.63 (1.16-2.30)e | 1.61 (1.24-2.09)d |
Note: Values in parentheses are 95% confidence intervals.
Abbreviations: BMI, body mass index; HR, hazard ratio; KFRT, kidney failure with replacement therapy; SD, standard deviation; WHR, waist-to-hip ratio.
Centered at median of each race-sex group.
Model 1 is random-effects model showing rate of decline (the interaction of each variable with follow-up time) adjusted for age (continuous), center (categorical), current smoker (yes/no), and prevalent coronary heart disease (yes/no) at baseline; model 2 additionally adjusted for hypertension medication (yes/no), systolic blood pressure (continuous), total cholesterol level (continuous), high-density lipoprotein cholesterol level (continuous), triglyceride level (continuous, log transformed), estimated glomerular filtration rate (continuous), education level (high school graduate/not graduated), and annual family income (categorical) at baseline.
Black participants in the Minnesota and Washington County centers were excluded in the model because of small numbers.
P < 0.01.
P < 0.001.
P < 0.05.