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. 2021 Feb 24;11:10. doi: 10.1038/s41387-021-00151-6

Table 1.

Baseline demographics and clinical characteristics of individuals with and without type 2 diabetes remission, from LABS and LookAHEAD cohorts combined.

Non-Remitters Remitters p
n 86 87
Intervention (%) 0.03
AGB 17 (19.8) 5 (5.7)
RYGB 29 (33.7) 42 (48.3)
DSE 7 (8.1) 7 (8.0)
ILI 33 (38.4) 33 (37.9)
Age (years) 54.95 (8.75) 53.28 (9.25) 0.22
Female (%) 62 (72.1) 56 (64.4) 0.35
White (%) 62 (72.1) 73 (83.9) 0.09
Baseline HbA1c (%) 7.21 (1.27) 6.44 (0.79) <0.001
HbA1c at yr 2 (%) 6.73 (1.02) 5.38 (0.40) <0.001
HbA1c at yr 4/5 (%) 7.12 (1.27) 5.46 (0.43) <0.001
Baseline BMI (kg/m2) 43.5 (6.6) 44.6 (7.6) 0.33
Weight change at yr 2 (%) −14.5 (13.4) −23.8 (13.1) <0.001
Weight change at yr 4/5 (%) −12.6 (14.5) −20.8 (13.3) <0.001
Waist circumference (cm) 128.4 (16.4) 130.9 (17.2) 0.32
Fasting glucose (mg/dl) 144.4 (51.0) 127.7 (31.5) 0.01
Fasting insulin (uU/ml) 25.1 (22.4) 24.4 (14.4) 0.80
HOMA-IR 7.54 (8.26) 7.68 (4.61) 0.9
HOMA-B 113.9 (75.0) 165.8 (138.1) 0.008
CHOL (mg/dl) 183.4 (36.9) 184.9 (38.1) 0.78
HDL (mg/dl) 42.9 (10.1) 41.4 (11.3) 0.35
LDL (mg/dl) 104.4 (34.4) 102.8 (31.8) 0.76
TRIG (mg/dl) 188.4 (103.4) 222.9 (173.0) 0.11
Serum creatinine (mg/L) 0.79 (0.25) 0.82 (0.27) 0.47
hs-CRP (mg/L) 0.75 (1.03) 0.74 (0.83) 0.92
Metformin use at baseline (%) 55 (64.7) 48 (55.2)
0.26
# Non-insulin T2D meds at baseline (%) 0.03
0 13 (15.3) 24 (27.6)
1 40 (47.1) 42 (48.3)
2 22 (25.9) 19 (21.8)
3 10 (11.8) 2 (2.3)
Using insulin at baseline (%) 24 (27.9) 4 (4.6) <0.001

Data presented as mean (SD) for continuous variables and n (%) for categorical variables. AGB adjustable gastric banding, RYGB Roux-en-Y gastric bypass, ILI intensive life style intervention, DSE diabetes education.