Table 2.
Baseline demographics and clinical characteristics of individuals in best and worst weight loss groups (LABS study only).
| Best weight loss | Worst weight loss | p | |
|---|---|---|---|
| n | 75 | 76 | |
| Intervention (%) | |||
| AGB | 55 (73.3) | 56 (73.7) | |
| RYGB | 20 (26.7) | 20 (26.3) | |
| Age (years) | 46.0 (11.4) | 47.7 (10.3) | 0.34 |
| Female (%) | 63 (84.0) | 60 (78.9) | 0.56 |
| White (%) | 63 (84.0) | 70 (92.1) | 0.20 |
| Baseline HbA1c (%) | 5.88 (0.90) | 5.96 (1.10) | 0.63 |
| HbA1c at yr 2 (%) | 5.14 (0.41) | 5.46 (0.75) | 0.001 |
| HbA1c at yr 5 (%) | 5.14 (0.45) | 5.80 (1.06) | <0.001 |
| Baseline BMI (kg/m2) | 49.2 (7.8) | 47.3 (6.9) | 0.11 |
| Weight change at yr 2 (%) | −40.0 (11.0) | −18.6 (11.6) | <0.001 |
| Weight change at yr 5 (%) | −42.1 (5.9) | −8.5 (8.7) | <0.001 |
| Waist circumference (cm) | 134.5 (16.9) | 132.8 (16.8) | 0.54 |
| Fasting glucose (mg/dl) | 106.8 (29.3) | 110.2 (35.6) | 0.53 |
| Fasting insulin (uU/ml) | 26.5 (25.7) | 21.5 (14.2) | 0.14 |
| HOMA-IR | 6.38 (4.47) | 5.79 (4.68) | 0.44 |
| HOMA-B | 227.4 (160.0) | 212.0 (137.1) | 0.54 |
| CHOL (mg/dl) | 184.1 (32.1) | 182.9 (34.3) | 0.82 |
| HDL (mg/dl) | 45.3 (11.2) | 43.6 (11.8) | 0.38 |
| LDL (mg/dl) | 108.7 (27.1) | 109.7 (28.6) | 0.83 |
| TRIG (mg/dl) | 150.5 (63.3) | 147.8 (68.7) | 0.80 |
| Serum creatinine (mg/L) | 0.78 (0.28) | 0.75 (0.22) | 0.44 |
| hs-CRP (mg/L) | 1.26 (1.42) | 0.94 (1.13) | 0.13 |
| Metformin use at baseline (%) | 11 (17.2) | 20 (29.9) | 0.13 |
| # Non-insulin diabetes meds at baseline (%) | 0.35 | ||
| 0 | 45 (77.6) | 39 (62.9) | |
| 1 | 7 (12.1) | 14 (22.6) | |
| 2 | 5 (8.6) | 7 (11.3) | |
| 3 | 1 (1.7) | 2 (3.2) | |
| Using insulin at baseline (%) | 5 (6.9) | 4 (5.5) | 0.98 |
Data presented as mean (SD) for continuous variables and n (%) for categorical variables. AGB adjustable gastric banding, RYGB Roux-en-Y gastric bypass.