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. 2021 Feb 24;12:1264. doi: 10.1038/s41467-021-21541-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — We collected ten reference panels of differing ethnicities and sizes. We then tested every possible pair by assigning one panel as a reference and another as a target, which comprised 88 tests after excluding overlapping sample pairs. We compared the full version of CookHLA to CookHLA-HapMap (upgraded engine, with HapMap genetic map). The dotted line indicates where the two methods’ imputation accuracies are equal.