Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 24;12:1269. doi: 10.1038/s41467-021-21247-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a Telomere repeats in ChIP of H3K9me3 (n = 26), H3K27ac (n = 25), H3K27me3 (n = 25) and H3K36me3 (n = 27) relative to telomere repeats in input of ALT-positive and ALT-negative tumors. b–e Protein and mRNA expression of KDM1A (b), SETDB1 (c), SUV39H1/H2 (d, only RNA), and EZH2 (e) in ALT tumors compared to tumors form the other groups (TERT, MNA, OTHER). a–e Colors indicate subgrouping based on presence and type of telomere maintenance mechanism (see legend). Boxplots indicate the median value (middle line) and the 25th and 75th percentiles (box). The upper/lower whisker spans from the hinge to the largest/smallest value (values expanding a distance of 1.5 x inter quartile range are not considered). Dots represent individual tumors. P values were calculated using a two-sided Wilcoxon rank sum test. n describes the number of analyzed tumors.