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. 2021 Feb 24;11:4494. doi: 10.1038/s41598-020-80425-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Representative transmission electron microscopy (TEM) images of cerebellar mitochondria. The circular, granular and tubular shaped mitochondria were frequently observed in the mice in normal control group (a), SHH5000 group (b), and SHH8000 group (c). Results showed that mitochondrial morphology in cerebellum did not significantly change after SHH treatment. Scale bars, 500 nm.