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. 2021 Feb 24;12:1278. doi: 10.1038/s41467-021-21529-1

Fig. 2. Transcription-dependent regulation of 7SK/hnRNP/Smn complexes.

Fig. 2

a Western blot analysis of proteins co-immunoprecipitated by anti-Larp7 from NSC-34 cells treated with DMSO or actinomycin D (ActD) for 1 h. b Co-immunoprecipitation of Larp7 by anti-Smn from NSC-34 cells treated with DMSO or ActD for 1 h. c, d Co-immunoprecipitation of proteins by anti-Mepce from NSC-34 cells treated with DMSO or ActD for 1 h. For Western blots of hnRNP R and Cdk9, a shorter exposure of the inputs was chosen. e Co-immunoprecipitation of Larp7 by anti-Smn from cultured mouse primary motoneurons treated with DMSO or ActD for 6 h. f Co-immunoprecipitation of proteins by anti-SMN from HEK293TN cells treated with DMSO or ActD for 1 or 6 h. Source data are provided as a Source Data file.