Table 4.
Gene Ontology term enrichment analysis of the more differentially expressed genes.
| Term ID | Biological process | FDR | Genes |
|---|---|---|---|
| Immune system | |||
| GO:0002376 | Immune system process | 1.74E-07 | ABCA13, ARG1, CEACAM8, CRISP3, CYSLTR2, DDIT4, FLT3, IDO1, IL5RA, LTF, MMP8, MMP9, PI3, PTGDR2, RAB44, SMPD3. |
| GO:0006955 | Immune response | 5.94E-06 | ABCA13, ARG1, CEACAM8, CRISP3, CYSLTR2, IL5RA, LTF, MMP8, MMP9, PI3, PTGDR2, RAB44. |
| GO:0043312 | Neutrophil degranulation | 7.28E-05 | ABCA13, ARG1, CEACAM8, CRISP3, LTF, MMP8, MMP9, RAB44. |
| Cellular process | |||
| GO:0001775 | Cell activation | 1.32E-06 | ABCA13, ARG1, CEACAM8, CRISP3, FLT3, ITGA2B, LTF, MMP8, MMP9, PIK3R6, RAB44. |
| GO:0019221 | Cytokine-mediated signaling pathway | 8.10E-03 | ALOX15, FLT3, IL5RA, MMP9. |
| GO:0007166 | Cell surface receptor signaling pathway | 0.017 | ALOX15, DDIT4, FLT3, G0S2, GPR34, IL5RA, MMP9. |
| GO:0007165 | Signal transduction | 0.012 | ALOX15, CYSLTR2, DDIT4, FLT3, G0S2, GPR34, HRH4, IL5RA, MMP9, PIK3R6, PTGDR2. |
| Cellular response | |||
| GO:0050896 | Response to stimulus | 2.52E-06 | ABCA13, ALOX15, ARG1, CEACAM8, CRISP3, CYSLTR2, DDIT4, FLT3, G0S2, GPR34, HRH4, IDO1, IL5RA, ITGA2B, LTF, MMP8, MMP9, PER1, PI3, PIK3R6, PTGDR2, RAB44. |
| GO:0006952 | Defense response | 9.28E-05 | ALOX15, ARG1, CRISP3, DDIT4, HRH4, IDO1, IL5RA, LTF. |
| GO:0006950 | Response to stress | 3.00E-04 | ALOX15, ARG1, CRISP3, DDIT4, HRH4, IDO1, IL5RA, ITGA2B, LTF, MMP9, PIK3R6. |
| GO:0006954 | Inflammatory response | 2.50E-03 | ALOX15, HRH4, IDO1, IL5RA. |
| GO:0071345 | Cellular response to cytokine stimulus | 9.30E-03 | ALOX15, ARG1, FLT3, IL5RA, MMP9. |
| Biological regulation | |||
| GO:0048583 | Regulation of response to stimulus | 6.84E-05 | ALOX15, ARG1, CLC, CYSLTR2, DDIT4, FLT3, G0S2, HRH4, IDO1, LTF, MMP9, PER1, PIK3R6, PTGDR2. |
| GO:0009966 | Regulation of signal transduction | 6.84E-05 | ALOX15, ARG1, CYSLTR2, DDIT4, FLT3, G0S2, HRH4, LTF, MMP9, PER1, PIK3R6 PTGDR2. |
| GO:0051239 | Regulation of multicellular organismal process | 2.30E-04 | ARG1, CLC, CYSLTR2, IDO1, IL5RA, ITGA2B, LTF, MMP9, PER1, PIK3R6, PTGDR2. |
| GO:0001817 | Regulation of cytokine production | 6.20E-03 | ARG1, CLC, IDO1, IL5RA, LTF, PER1. |
| GO:0050794 | Regulation of cellular process | 0.018 | ALOX15, ARG1, CLC, CRY2, CYSLTR2, DDIT4, FLT3, G0S2, GPR34, HRH4, IDO1, IL5RA, ITGA2B, LTF, MMP9, PER1, PI3, PIK3R6, PTGDR2, SMPD3. |
FDR, false discovery rate.