Table 1.
Name | Discovery/location | Group | Receptor | Symptom |
---|---|---|---|---|
HCOV-229E | 1966 | α | Aminopeptidase N (hAPN, CD13) |
Common cold |
HCoV-OC43 | 1967 | ß | 9-O-acetylated sialic acid | Common cold |
SARS-CoV | 2003/china | ß | ACE2/CD209L | Severe respiratory illness |
HCoV-NL63 | 2004/Netherlands | α | ACE2 | Lower respiratory tract infection, croup and bronchiolitis in children and immunocompromised patients |
HCoV-HKU1 | 2005/HongKong | ß | 9-O-acetylated sialic acid | Chronic pulmonary disease in Hong Kong |
MERS-CoV | 2012/Middle East | ß | DPP4 | Severe respiratory illness |
Sars-Cov2 | 2019/China | ß | ACE2 | Severe respiratory illness |