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. 2021 Feb 11;15:638772. doi: 10.3389/fnins.2021.638772

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Copyright © 2021 Fu and Jia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ISL suppressed the morphological changes of BV2 cells exposed to AβO. BV2 cells were pre-treated with 20 μM ISL for 2 h and then co-treated with 5 μM AβO for 6 h. (A) Iba1 and Actin Red was used to assess the morphological changes of BV2 cells. (B) ISL treatment suppressed the morphological changes in BV2 cells induced by AβO. Scale bar: 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001.