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ISL attenuates oxidative stress in BV2 cells. (A,B) BV2 cells were pre-treated with ISL for 2 h and then treated with 5 μM AβO for 6 h. The mRNA levels of COX-2 and iNOS were analyzed by qRT-PCR. (C) BV2 cells were pre-treated with ISL for 2 h and then treated with 5 μM AβO for 24 h. The production of NO was assessed using the Griess reaction assay. *p < 0.05, **p < 0.01, ***p < 0.001. n = 6 per group.
