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. 2021 Feb 24;12(2):208. doi: 10.1038/s41419-021-03499-w

Fig. 5. El potentiated the efficacy of MSCs on anti-leukemia in vivo.

Fig. 5

A Schematic illustration of experimental design. B Representative images of spleens from four groups. C The weight of spleens in different groups. D Percentage of human CD45+ leukemia cells in peripheral blood (PB) and bone marrow (BM) in vehicle and treatment mice after 10 weeks of transplantation. E Human CD45+ cells from a single-cell suspension of peripheral blood were sorted using FASC. RT-qPCR analysis on FACS-isolated human CD45+ cells for CD41, CD42b, CD61. F Histologic sections of spleen were stained with hematoxylin-eosin. Scale bars, 100 μm. G Representative infiltration of CML cells in the spleen as observed via immunofluorescence with anti-CD45 antibody (green). Nuclei are stained with DAPI (blue). Scale bars, 100 μm. All statistical data in this figure showed the mean ± SEM (*P <0.05, **P <0.01, ***P <0.001; one-way ANOVA was used for multiple comparisons). El eltrombopag.