Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 24;11:4430. doi: 10.1038/s41598-021-83398-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Inward current in myofibroblasts causes slowing in co-cultured cardiomyocyte syncytia. (A) Activation maps of a co-culture of ChR2-MFBs with CMs before (i), during (ii), and after (iii) application of 3*I₀ blue light to activate ChR2 current in MFBs. Color bar at right shows activation time scale. Isochrones are 10 ms apart. Red pacing marker illustrates location of pacing. (B) Percent change (from value prior to light application) in conduction velocity (CV) during and after application of light at different power levels during 500 ms CL pacing, for co-cultures of CMs with MFBs or ChR2-MFBs. Data for 10*I₀ is not shown since almost all samples beat spontaneously with CL less than 500 ms at this intensity. * indicates p < 0.05, # indicates p < 0.005 between ChR2-MFB and MFB co-culture responses during light.