FIGURE 8.

Mito-apocynin reverses KA-induced upregulation of NOX4 in mitochondria fraction. (A–D) Animals were pre-treated with mito-apocynin (displayed as Mito-apo in figures; 6 mg/kg, i.g) 1 day prior to KA (0.625 nmol) injection and then they were sacrificed 6 h later for western blotting. Representative bands and semi-quantitation of western blots for detecting NOX4 protein levels. Data are expressed as the Mean ± SEM (n = 5. *P < 0.05; ^#P < 0.05 vs KA, one-way ANOVA, followed by a post hoc multiple comparison Student-Newman–Keuls test).