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. 2021 Feb 20;6(9):2841–2853. doi: 10.1016/j.bioactmat.2021.02.007

Fig. 4.

Fig. 4

Multiple functions of engineered miR-31 exosomes. (A) migration of ECs, HFF-1 cells and HaCaT cells; (B) proliferation of ECs, HFF-1 cells and HaCaT cells; (C) EC tube formation; *significant difference compared with control (p < 0.05); **significant difference compared with control (p < 0.01); ***significant difference compared with control (p < 0.001); ****significant difference compared with control (p < 0.0001); # significant difference compared with nonengineered HEK293 exosomes (p < 0.05); ## significant difference compared with nonengineered HEK293 exosomes (p < 0.01); ### significant difference compared with nonengineered HEK293 exosomes (p < 0.001); #### significant difference compared with nonengineered HEK293 exosomes (p < 0.0001).