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PRF1 expression and association with clinical parameters in HNSCC. PRF1 expression in the different T stage (A), N stage (B), clinical stage (C), tumor site (D) and HPV status (E). (F) Correlation of PRF1 and CDKN2A (P16) expression from TIMER. (G) Representative IHC images of PRF1 protein expression in tumor tissues and normal tissues in HNSCC. (H) Quantitative analysis of PRF1 in tumor and normal tissues. AOD, average optical density. (*p < 0.05, **p < 0.01, ***p < 0.001).
