Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 11;8:628473. doi: 10.3389/fcell.2020.628473

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Lliberos, Liew, Mansell and Hutt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Pro-inflammatory cytokine levels are reduced in the serum of aging Asc^−/− mice. Serum IL-6 (A) concentration measured in 2, 6, 12, and 18-month-old WT and Asc^−/− mice. Circulating levels of TNF-α (B) and IL-18 (C) determined in 2, 6, 12, and 18-month-old WT, Asc^−/−, and Nlrp3^−/− mice. n = 4–6 per cohort. ND, Not Determined. Data are presented as mean ± SEM. For each age group, comparisons were made with WT using Student's t-test (A,C) or Mann-Whitney test (A–C) (*p < 0.05, ****p < 0.0001).